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Fisher's exact (2×2)

§2.2
Rev 4.6 · reviewed Feb 2026
Fisher's exact test (2×2)
The exact alternative to chi-square when any expected cell count is small (< 5). No large-sample approximation — it enumerates every table with your margins.
Source formula: Fisher RA. Statistical Methods for Research Workers. 1925.
Table. Outcome by group
Outcome +Outcome −Total
Group 120
Group 220
Total103040
* Two-sided exact p by the sum of tables no more probable than observed. Fisher RA. Statistical Methods for Research Workers. 1925.
† Proportion CIs are Wilson intervals. Wilson EB. J Am Stat Assoc 1927;22:209–12.
Group 1 proportion (95% CI)†
10.0% (2.8%–30.1%)
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Group 2 proportion (95% CI)†
40.0% (21.9%–61.3%)
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Odds ratio
0.17
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Two-sided exact p
0.065
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With exact p = 0.065, this sample doesn't show a significant difference. With small counts, absence of significance is especially weak evidence of no effect — a wider study may be needed.
Understand what this is measuring